Found 22 matching trials
Fortifying Healthy Behaviors, Optimizing Medical Therapies and Enhancing Cognitive Function in Older Adults-pilot Study PHASE2 The purpose of this research study is to explore ways to improve motor, cog...
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Washington University School of Medicine
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Dasatinib and Quercetin With CAR-T Therapy for the Treatment of Patients With Relapsed or Refractory Multiple Myeloma PHASE2 This phase II trial tests how well giving dasatinib and quercetin with cycl...
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Mayo Clinic in Rochester
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Safety and Feasibility of Dasatinib and Quercetin in Adults at Risk for Alzheimer's Disease PHASE1 The purpose of this pilot study is to demonstrate the safety and feasibilit...
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Hebrew Senior Life
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Targeting Cellular Senescence With Senolytics to Improve Skeletal Health in Older Humans PHASE2 To determine if senolytic drugs reduce senescent cell burden and reduce bon...
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Mayo Clinic in Rochester
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Medication Combinations of Dasatinib, Quercetin, Fisetin, Temozolomide, LMP744, and Autologous TLPO Vaccine for the Treatment of Previously Treated Glioma With Residual Disease EARLY_PHASE1 This early phase I trial tests the safety, side effects and how well medica...
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Mayo Clinic in Rochester
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Senolytic Therapy to Modulate the Progression of Alzheimer's Disease (SToMP-AD) Study PHASE2 The objective of the study is to determine the safety, feasibility, and eff...
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Active Not Recruiting
Location
Wake Forest Health Sciences
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Senolytics to Improve Osteoporosis Therapy PHASE2 This randomised clinical trial aims to study osteoporosis as a disease of a...
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Active Not Recruiting
Location
Odense University Hospital
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Improving Physical Ability and Cellular Senescence Elimination in HIV PHASE2 This clinical trial is a Phase II study designed to test the safety and eff...
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Active Not Recruiting
Location
University of California, Los Angeles CARE Center CRS (Site ID: 601)
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Single Nuclei RNA-seq to Map Adipose Cellular Populations and Senescent Cells in Older Subjects PHASE2 All participants will undergo baseline biopsies of subcutaneous abdominal a...
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Cedars Sinai Medical Center
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Hematopoietic Stem Cell Transplant Survivors Study PHASE1 The investigators hope to find the proof of principle concept from this pil...
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Mayo Clinic in Rochester
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